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1996-02-27
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Document 0632
DOCN M9630632
TI [Neuropsychological development of children born to HIV-positive
mothers]
DT 9603
AU Piazza F; Astori MG; Maccabruni A; Caselli D; Bossi G; Lanzi G; Istituto
Neurologico C. Mondino di Pavia, Italia.
SO Pediatr Med Chir. 1995 Jul-Aug;17(4):331-3. Unique Identifier : AIDSLINE
MED/96093231
AB 138 children born to HIV infected mothers (58 HIV infected and 80
seroreverted uninfected) were followed up at the Institute of Infectious
Diseases of the University of Pavia. All patients had an evaluation of
neurological assessment every three months done by a pediatric
neurologist (Amiel-Tison and Towen) and an evaluation of psychological
assessment by observation of child-mother interaction. The development
quotient was examined using the Griffiths Scales and mental development
using the Wisc-R scale. The incidence of Central Nervous System
involvement was 36% in children with symptomatic HIV infection, the hump
of incidence of severe encephalopathy was in the first 4 or 5 year of
life, another hump (smaller) was in preadolescence. Development deficit
and psychological problems were discovered both in asymptomatic infected
and in non infected children, without difference of percentage between
the two groups.
DE Acquired Immunodeficiency Syndrome/PSYCHOLOGY/TRANSMISSION Age Factors
Central Nervous System Diseases/*DIAGNOSIS Child *Child Development
Child, Preschool Comparative Study English Abstract Female Human
HIV Infections/PSYCHOLOGY/*TRANSMISSION *HIV Seropositivity Infant
Infant, Newborn Male Pregnancy *Pregnancy Complications, Infectious
Psychological Tests JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).